Progesterone concentration in rabbit uterine flushings before implantation.
نویسندگان
چکیده
Uteroglobin (or blastokinin) is a specific protein produced by rabbit endometrium when stimulated by exogenous or endogenous progesterone (Schwick, 1965; Beier, 1968a, b; Krishnan & Daniel, 1967; Urzua, Stambaugh, Flickinger & Mastroianni, 1970; Arthur & Daniel, 1972; Bullock & Connell, 1973). The protein is known to bind steroids, particularly progesterone (Urzua et al., 1970; Arthur & Daniel, 1972; Beato & Baier, 1975), and its role in early rabbit embryonic development may be that of a carrier protein for progesterone (Arthur, Cowan & Daniel, 1972; El Banna & Daniel, 1972a, b; Beato & Baier, 1975). Progesterone can be detected in 5and 6-day post coitum rabbit blastocysts, 7-, 8and 9-day post coitum blastocoelic fluid and in uterine washings from 5-day pseudopregnant rabbits (Beier, 1968b; Seamark & Lutwak-Mann, 1972). We now report measurements of the concentration of progesterone in non-pregnant and pregnant rabbit uterine flushings and plasma.
منابع مشابه
Partial purification and characterization of a trypsin-like proteinase from rabbit preimplantation uterine fluid.
Previous investigations have proved that proteinases are involved in implantation of the rabbit embryo into the uterine tissues. This study describes a trypsin-like enzyme found in the blastocyst fluid and uterine flushings at the time of implantation. The proteinase isolated from uterine flushings has a molecular mass of about 50 kDa and exists in two differently charged forms of pI 4.0 and 4....
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ورودعنوان ژورنال:
- Journal of reproduction and fertility
دوره 47 2 شماره
صفحات -
تاریخ انتشار 1976